![]() That Band 23 was part of the half of the test called IgM (Immunoglobulin M), which means the antibodies that appear relatively soon after infection. Nothing else but Lyme, to my understanding, will cause Band 23 to be positive. Band 23, on which you are positive, will show up ONLY if the test detects Borrelia burgdorferi (Bb), which is the Lyme bacterium. :) Okay, so you had WBlot through LabCorp. Wow, your doc DOES work fast! I like this doc. This thing is a couple rungs up the evolutionary ladder. ![]() As one researcher has said, this is not your run of the mill bacteria. It sounds to me like the cysts were protected Lyme factories that the antibiotics and immune system couldn't get to. In both cases, after they took the cysts out surgically, the cysts tested positive for spirochetes, and then the patients stopped relapsing. In the other, I think the cyst was next to a lymph node. Another example of hiding: I have read two unusual stories of patients who repeatedly relapsed after treatment. There are major differences of course.Lyme is bacterial and curable with abx. I suspect this is why some doctors who previously researched and treated AIDS got interested in Lyme. There was also a video shown of a spirochete going into a human cell, and then coming out wrapped in the human mucus so it would not be recognized as foreign. A researcher presented actual pictures at an ILADS conference of a spirochete rotating its way into an immune cell. Eva Sapi has done some really interesting research with this, as well as in vitro studies on different abx for treatment. This is called the cell wall deficient form or L-form version. The spirochetes are known to invade our own cells to hide, and also to turn themselves almost inside out to hide their outer proteins, which is what the antibodies go after. But immune systems are not simple machines that follow a recipe. Eventually, sometime after the bacteria is gone, IgG antibodies go away. Theoretically, the IgM antibody production drops and IgG antibody production ramps up about 4-6 weeks after initial infection. Lyme can also hide in the body, resulting in decreased antibody production. My PA explained that over time, as the spirochetes move out of the blood and into tissues, the concentration of spirochetes in the blood drops, leading the body to reduce antibody production, sometimes too low to be detected. It's no wonder I wasn't showing a strong immune response on antibody tests. Years later when I finally developed chronic symptoms, I was given some prednisone for my supposed asthma, which further suppressed my immune system. That is known to interfere with antibody production. My situation is complicated as I had a week of abx when I first got sick. They look at both for Borrelia specific antibodies, regardless of where they show up. They have seen way too many variations in immune system responses. My LLMD and PA have no such requirement of IgM or IgG. I think what you describe of converting from IgM to IgG is what the immune system is expected to do. Thank you, and ANY help is so much appreciated!!! I was unsure why he asked me to come in for more blood work today after my Western blot a week or so ago I found out he is sending out my blood to another lab that will grow a T cell and then see if it attacks Lyme, to see if my T cell has a memory of it, so to speak. How many have had this happen? Furthermore couldn't it mean I DO have more bands possibly present, but because Lyme isn't often in the blood, they may not be showing? Perhaps if I did Igenix I'd get a more complete picture? UPDATE on 2nd lab Doctor is running that I talked about in another post. 2) Now, I've heard some people will have one band on one Western Blot, and then the next time that band is absent, but another band Present/ abnormal. He says your body just doesn't 'make' antibodies to Lyme without it present. But why do they want at least a few? Could my 23 band be something else? According to my doctor he canNOT ignore band 23. CD8-CD57 +Lymphs 60 (in range 60-360) My questions/ comments: 1) Why does the CDC ask for 5 bands total? I understand it was based on early research and at the time those first groups of people with the 'typical' lyme symptoms presented these specific bands. Hi guys, For those interested, I am posting my Western Blot lab results from LabCorp: It is as follows: IgM: Bands: 41 Absent 39 Absent 23 PRESENT ABNORMAL IgG Bands: 93, 66, 58, 45, 41, 39, 30, 28, 23, 18 -> ALL ABSENT % CD8-/CD57 Lymphs is 5.0 (in range 2.0-17.0) Abs.
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